Courses

The core also provides a resource for training and expertise in macromolecular crystallography techniques through informal consultations or through participation in a class/workshop “Practical Protein Crystallography” - BIOC 587. The aim of the class is to provide training and practical knowledge on preparing proteins for crystallization, growing of protein crystals, techniques of cryocrystallography, data collection and processing, and selected aspects of protein structure determination.   

BIOC 585 Biological Structure I (4 units) Introduction to the current understanding and methods used for study of the structure, thermodynamics, and dynamics of proteins, nucleic acids, and membranes. Prerequisites include BIOC 462A; BIOC 565, CHEM 480B, or permission of instructor. Identical to CHEM 585, MCB 585. Usually offered in the Spring.

BIOC 587 Practical Macromolecular Crystallography (1 unit) Concomitant with BIOC 585. Provides practical experience in protein crystallization and cryocrystallography methods. Students conduct individual X-ray diffraction experiments followed by structure solution and refinement exercises. Regular grades are awarded for this course. Available to qualified students for Pass/Fail Option. Prerequisite(s):  BIOC 585 or consent of instructor. Usually offered in the Spring.